Mistral Medium 3.5 vs Nemotron 4 340B
Mistral Medium 3.5 (2026) and Nemotron 4 340B (2025) are frontier reasoning models from MistralAI and NVIDIA AI. Mistral Medium 3.5 ships a 256k-token context window, while Nemotron 4 340B ships a 4k-token context window. On pricing, Mistral Medium 3.5 costs $1.50/1M input tokens versus $4.20/1M for the alternative. This comparison covers specs, pricing, API access, capabilities, benchmarks, input and output token costs, and production fit for coding and agent workloads.
Mistral Medium 3.5 is ~180% cheaper at $1.50/1M; pay for Nemotron 4 340B only for provider fit.
Decision scorecard
Local evidence first| Signal | Mistral Medium 3.5 | Nemotron 4 340B |
|---|---|---|
| Best for | reasoning-heavy apps, multimodal apps, and tool-calling agents | provider-routed production |
| Decision fit | Coding, RAG, and Agents | Classification and JSON / Tool use |
| Context window | 256k | 4k |
| Cheapest output | $7.50/1M tokens | $4.20/1M tokens |
| Provider routes | 3 tracked | 2 tracked |
| Shared benchmarks | 0 rows | 0 rows |
Decision tradeoffs
- Mistral Medium 3.5 has the larger context window for long prompts, retrieval packs, or transcript analysis.
- Mistral Medium 3.5 has broader tracked provider coverage for fallback and procurement flexibility.
- Mistral Medium 3.5 uniquely exposes Vision, Multimodal, and Reasoning in local model data.
- Local decision data tags Mistral Medium 3.5 for Coding, RAG, and Agents.
- Nemotron 4 340B has the lower cheapest tracked output price at $4.20/1M tokens.
- Local decision data tags Nemotron 4 340B for Classification and JSON / Tool use.
Monthly cost at traffic
Estimate token spend from the cheapest tracked input and output route or tier on this page.
Mistral Medium 3.5
$3,075
Cheapest tracked route/tier: Mistral AI Studio
Nemotron 4 340B
$4,410
Cheapest tracked route/tier: DeepInfra
Estimated monthly gap: $1,335. Batch, cache, alternate speed tiers, and negotiated pricing are excluded from this local estimate.
Switch friction
- No overlapping tracked provider route is sourced for Mistral Medium 3.5 and Nemotron 4 340B; plan for SDK, billing, or endpoint changes.
- Nemotron 4 340B is $3.30/1M tokens lower on cheapest tracked output pricing before cache, batch, or negotiated discounts.
- Check replacement coverage for Vision, Multimodal, and Reasoning before moving production traffic.
- No overlapping tracked provider route is sourced for Nemotron 4 340B and Mistral Medium 3.5; plan for SDK, billing, or endpoint changes.
- Mistral Medium 3.5 is $3.30/1M tokens higher on cheapest tracked output pricing, so quality gains need to justify the spend.
- Mistral Medium 3.5 adds Vision, Multimodal, and Reasoning in local capability data.
Specs
| Specification | ||
|---|---|---|
| Released | 2026-04-29 | 2025-02-27 |
| Context window | 256k | 4k |
| Parameters | 128B | 340B |
| Architecture | decoder only | decoder only |
| License | Proprietary | NVIDIA Open Model |
| Openness | Proprietary | Open weights |
| Commercial use | Commercial use with conditions | Commercial use allowed |
| Knowledge cutoff | - | - |
Pricing and availability
| Pricing attribute | Mistral Medium 3.5 | Nemotron 4 340B |
|---|---|---|
| Input price | $1.50/1M tokens | $4.20/1M tokens |
| Output price | $7.50/1M tokens | $4.20/1M tokens |
| Providers |
Capabilities
| Capability | Mistral Medium 3.5 | Nemotron 4 340B |
|---|---|---|
| Vision | Yes | No |
| Multimodal | Yes | No |
| Reasoning | Yes | No |
| Function calling | Yes | No |
| Tool use | Yes | No |
| Structured outputs | Yes | Yes |
| Code execution | No | No |
| IDE integration | No | No |
| Computer use | No | No |
| Parallel agents | No | No |
Benchmarks
No shared benchmark rows are currently sourced for this pair.
Deep dive
The capability footprint differs most on vision: Mistral Medium 3.5, multimodal input: Mistral Medium 3.5, reasoning mode: Mistral Medium 3.5, function calling: Mistral Medium 3.5, and tool use: Mistral Medium 3.5. Both models share structured outputs, so the practical split is not just feature count. Use those differences to decide whether the page is about raw model quality, agentic coding support, multimodal ingestion, or predictable structured API behavior.
For cost, Mistral Medium 3.5 lists $1.50/1M input and $7.50/1M output tokens on the cheapest tracked provider, while Nemotron 4 340B lists $4.20/1M input and $4.20/1M output tokens on the cheapest tracked provider. A 70/30 input-output blend puts Mistral Medium 3.5 lower by about $0.90 per million blended tokens. Availability is 3 providers versus 2, so concentration risk also matters.
Choose Mistral Medium 3.5 when reasoning depth, larger context windows, and lower input-token cost are central to the workload. Choose Nemotron 4 340B when provider fit are more important. For production, rerun your own prompts through the exact provider, region, and tool stack you plan to ship. This keeps the decision grounded in measurable tradeoffs instead of brand-level assumptions.
FAQ
Which has a larger context window, Mistral Medium 3.5 or Nemotron 4 340B?
Mistral Medium 3.5 supports 256k tokens, while Nemotron 4 340B supports 4k tokens. That gap matters most for long documents, large codebases, retrieval-heavy agents, and conversations where earlier context must remain visible.
Which is cheaper, Mistral Medium 3.5 or Nemotron 4 340B?
Mistral Medium 3.5 is cheaper on tracked token pricing. Mistral Medium 3.5 costs $1.50/1M input and $7.50/1M output tokens. Nemotron 4 340B costs $4.20/1M input and $4.20/1M output tokens. Provider discounts or batch pricing can still change the final bill.
Is Mistral Medium 3.5 or Nemotron 4 340B open source?
Mistral Medium 3.5 is listed under Proprietary. Nemotron 4 340B is listed under NVIDIA Open Model. License labels affect whether you can self-host, redistribute weights, or rely only on hosted APIs, so confirm the upstream license before deployment.
Which is better for vision, Mistral Medium 3.5 or Nemotron 4 340B?
Mistral Medium 3.5 has the clearer documented vision signal in this comparison. If vision is mission-critical, validate it against the provider endpoint because model-level support and API-level exposure can differ.
Which is better for multimodal input, Mistral Medium 3.5 or Nemotron 4 340B?
Mistral Medium 3.5 has the clearer documented multimodal input signal in this comparison. If multimodal input is mission-critical, validate it against the provider endpoint because model-level support and API-level exposure can differ.
Where can I run Mistral Medium 3.5 and Nemotron 4 340B?
Mistral Medium 3.5 is available on Mistral AI Studio, OpenRouter, and Vercel AI Gateway. Nemotron 4 340B is available on NVIDIA NIM and DeepInfra. Provider coverage can affect latency, region availability, compliance posture, and fallback options.
Continue comparing
Last reviewed: 2026-05-22. Data sourced from public model cards and provider documentation.