Claude Opus 4.5 vs Gemma 4 E2B IT
Claude Opus 4.5 (2025) and Gemma 4 E2B IT (2026) are frontier reasoning models from Anthropic and Google DeepMind. Claude Opus 4.5 ships a 200K-token context window, while Gemma 4 E2B IT ships a 128k-token context window. On MMLU PRO, Claude Opus 4.5 leads by 28.9 pts. This comparison covers specs, pricing, capabilities, benchmarks, provider availability, and production fit. It focuses on practical selection signals rather than broad model-family marketing.
Gemma 4 E2B IT is safer overall; choose Claude Opus 4.5 when coding workflow support matters.
Specs
| Specification | ||
|---|---|---|
| Released | 2025-11-01 | 2026-03-31 |
| Context window | 200K | 128k |
| Parameters | — | 2B |
| Architecture | decoder only | - |
| License | Proprietary | Open Source |
| Knowledge cutoff | 2025-12 | - |
Pricing and availability
| Pricing attribute | Claude Opus 4.5 | Gemma 4 E2B IT |
|---|---|---|
| Input price | $5/1M tokens | - |
| Output price | $25/1M tokens | - |
| Providers |
Capabilities
| Capability | Claude Opus 4.5 | Gemma 4 E2B IT |
|---|---|---|
| Vision | Yes | No |
| Multimodal | Yes | Yes |
| Reasoning | Yes | No |
| Function calling | Yes | Yes |
| Tool use | Yes | No |
| Structured outputs | Yes | Yes |
| Code execution | Yes | No |
Benchmarks
| Benchmark | Claude Opus 4.5 | Gemma 4 E2B IT |
|---|---|---|
| MMLU PRO | 88.9 | 60.0 |
Deep dive
On shared benchmark coverage, MMLU PRO has Claude Opus 4.5 at 88.9 and Gemma 4 E2B IT at 60, with Claude Opus 4.5 ahead by 28.9 points. The largest visible gap is 28.9 points on MMLU PRO, which matters most when that benchmark mirrors your workload. Treat isolated benchmark wins as directional, because provider routing, prompt style, and tool access can move real application results.
The capability footprint differs most on vision: Claude Opus 4.5, reasoning mode: Claude Opus 4.5, tool use: Claude Opus 4.5, and code execution: Claude Opus 4.5. Both models share multimodal input, function calling, and structured outputs, so the practical split is not just feature count. Use those differences to decide whether the page is about raw model quality, agentic coding support, multimodal ingestion, or predictable structured API behavior.
Pricing coverage is uneven: Claude Opus 4.5 has $5/1M input tokens and Gemma 4 E2B IT has no token price sourced yet. Provider availability is 5 tracked routes versus 2. Treat unknown pricing as an integration gap, then verify the route you will actually call before estimating production spend.
Choose Claude Opus 4.5 when coding workflow support, larger context windows, and broader provider choice are central to the workload. Choose Gemma 4 E2B IT when provider fit are more important. For production, rerun your own prompts through the exact provider, region, and tool stack you plan to ship.
FAQ
Which has a larger context window, Claude Opus 4.5 or Gemma 4 E2B IT?
Claude Opus 4.5 supports 200K tokens, while Gemma 4 E2B IT supports 128k tokens. That gap matters most for long documents, large codebases, retrieval-heavy agents, and conversations where earlier context must remain visible.
Is Claude Opus 4.5 or Gemma 4 E2B IT open source?
Claude Opus 4.5 is listed under Proprietary. Gemma 4 E2B IT is listed under Open Source. License labels affect whether you can self-host, redistribute weights, or rely only on hosted APIs, so confirm the upstream license before deployment.
Which is better for vision, Claude Opus 4.5 or Gemma 4 E2B IT?
Claude Opus 4.5 has the clearer documented vision signal in this comparison. If vision is mission-critical, validate it against the provider endpoint because model-level support and API-level exposure can differ.
Which is better for multimodal input, Claude Opus 4.5 or Gemma 4 E2B IT?
Both Claude Opus 4.5 and Gemma 4 E2B IT expose multimodal input. The better choice depends on benchmark fit, context budget, pricing, and whether your provider route exposes the same capability surface.
Which is better for reasoning mode, Claude Opus 4.5 or Gemma 4 E2B IT?
Claude Opus 4.5 has the clearer documented reasoning mode signal in this comparison. If reasoning mode is mission-critical, validate it against the provider endpoint because model-level support and API-level exposure can differ.
Where can I run Claude Opus 4.5 and Gemma 4 E2B IT?
Claude Opus 4.5 is available on Microsoft Foundry, Anthropic, GCP Vertex AI, AWS Bedrock, and OpenRouter. Gemma 4 E2B IT is available on Google AI Studio and GCP Vertex AI. Provider coverage can affect latency, region availability, compliance posture, and fallback options.
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Last reviewed: 2026-05-11. Data sourced from public model cards and provider documentation.