Claude Opus 4.5 vs Gemma 4 E2B
Claude Opus 4.5 (2025) and Gemma 4 E2B (2026) are frontier reasoning models from Anthropic and Google DeepMind. Claude Opus 4.5 ships a 200k-token context window, while Gemma 4 E2B ships a 128k-token context window. On MMMU Pro, Claude Opus 4.5 leads by 29.7 pts. This comparison covers specs, pricing, API access, capabilities, benchmarks, input and output token costs, and production fit for coding and agent workloads.
Gemma 4 E2B is safer overall; choose Claude Opus 4.5 when coding workflow support matters.
Decision scorecard
Local evidence first| Signal | Claude Opus 4.5 | Gemma 4 E2B |
|---|---|---|
| Best for | reasoning-heavy apps, multimodal apps, and tool-calling agents | multimodal apps, tool-calling agents, and provider-routed production |
| Decision fit | Coding, RAG, and Agents | RAG, Agents, and Long context |
| Context window | 200k | 128k |
| Cheapest output | $25/1M tokens | - |
| Provider routes | 6 tracked | 2 tracked |
| Shared benchmarks | MMMU Pro leader | 1 shared |
Decision tradeoffs
- Claude Opus 4.5 holds a shared-benchmark lead on MMMU Pro, ahead by 29.7 points.
- Claude Opus 4.5 has the larger context window for long prompts, retrieval packs, or transcript analysis.
- Claude Opus 4.5 has broader tracked provider coverage for fallback and route flexibility.
- Claude Opus 4.5 uniquely exposes Vision, Reasoning, and Structured outputs in local model data.
- Local decision data tags Claude Opus 4.5 for Coding, RAG, and Agents.
- Local decision data tags Gemma 4 E2B for RAG, Agents, and Long context.
Monthly cost at traffic
Estimate token spend from the cheapest tracked input and output route or tier on this page.
Claude Opus 4.5
$10,250
Cheapest tracked route/tier: Microsoft Foundry
Gemma 4 E2B
Unavailable
No complete token price in local provider data
Cost delta unavailable until both models have sourced input and output token prices.
Switch friction
- Provider overlap exists on GCP Vertex AI and AWS Bedrock; start route-level A/B tests there.
- Check replacement coverage for Vision, Reasoning, and Structured outputs before moving production traffic.
- Provider overlap exists on GCP Vertex AI and AWS Bedrock; start route-level A/B tests there.
- Claude Opus 4.5 adds Vision, Reasoning, and Structured outputs in local capability data.
Specs
| Specification | ||
|---|---|---|
| Released | 2025-11-01 | 2026-03-31 |
| Context window | 200k | 128k |
| Parameters | — | 2B |
| Architecture | Decoder Only | - |
| License | Proprietary | Apache 2.0OSI-approved |
| Openness | Proprietary | Open source |
| Weights | Not released | Available |
| Code | Unknown | Unknown |
| Commercial use | Commercial use: conditional | Commercial use: permitted |
| Knowledge cutoff | 2025-12 | 2025-01 |
Pricing and availability
| Pricing attribute | Claude Opus 4.5 | Gemma 4 E2B |
|---|---|---|
| Input price | $5/1M tokens | - |
| Output price | $25/1M tokens | - |
| Providers |
Capabilities
| Capability | Claude Opus 4.5 | Gemma 4 E2B |
|---|---|---|
| Vision | Yes | No |
| Multimodal | Yes | Yes |
| Reasoning | Yes | No |
| JSON / Tool use | Yes | Yes |
| Structured outputs | Yes | No |
| Code execution | Yes | No |
| IDE integration | No | No |
| Computer use | No | No |
| Parallel agents | No | No |
Benchmarks
| Benchmark | Claude Opus 4.5 | Gemma 4 E2B |
|---|---|---|
| MMMU Pro | 73.9 | 44.2 |
Continue comparing
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Last reviewed: 2026-07-26. Data sourced from public model cards and provider documentation.