LLM Reference

Llama 3.1 405B Instruct vs Mistral NeMo (2407)

Llama 3.1 405B Instruct (2024) and Mistral NeMo (2407) (2024) are compact production models from AI at Meta and MistralAI. Llama 3.1 405B Instruct ships a 128k-token context window, while Mistral NeMo (2407) ships a 128k-token context window. On pricing, Mistral NeMo (2407) costs $0.02/1M input tokens versus $2.40/1M for the alternative. This comparison covers specs, pricing, API access, capabilities, benchmarks, input and output token costs, and production fit for coding and agent workloads.

Mistral NeMo (2407) is ~11900% cheaper at $0.02/1M; pay for Llama 3.1 405B Instruct only for provider fit.

Decision scorecard

Local evidence first
SignalLlama 3.1 405B InstructMistral NeMo (2407)
Best forprovider-routed productionprovider-routed production
Decision fitRAG, Long context, and ClassificationLong context
Context window128k128k
Cheapest output$2.40/1M tokens$0.03/1M tokens
Provider routes11 tracked7 tracked
Shared benchmarks0 shared0 shared

Decision tradeoffs

Choose Llama 3.1 405B Instruct when...
  • Llama 3.1 405B Instruct has broader tracked provider coverage for fallback and procurement flexibility.
  • Llama 3.1 405B Instruct uniquely exposes Structured outputs in local model data.
  • Local decision data tags Llama 3.1 405B Instruct for RAG, Long context, and Classification.
Choose Mistral NeMo (2407) when...
  • Mistral NeMo (2407) has the lower cheapest tracked output price at $0.03/1M tokens.
  • Local decision data tags Mistral NeMo (2407) for Long context.

Monthly cost at traffic

Estimate token spend from the cheapest tracked input and output route or tier on this page.

Lower estimate Mistral NeMo (2407)

Llama 3.1 405B Instruct

$2,520

Cheapest tracked route/tier: AWS Bedrock

Mistral NeMo (2407)

$23.50

Cheapest tracked route/tier: OpenRouter

Estimated monthly gap: $2,497. Batch, cache, alternate speed tiers, and negotiated pricing are excluded from this local estimate.

Switch friction

Llama 3.1 405B Instruct -> Mistral NeMo (2407)
  • Provider overlap exists on Fireworks AI; start route-level A/B tests there.
  • Mistral NeMo (2407) is $2.37/1M tokens lower on cheapest tracked output pricing before cache, batch, or negotiated discounts.
  • Check replacement coverage for Structured outputs before moving production traffic.
Mistral NeMo (2407) -> Llama 3.1 405B Instruct
  • Provider overlap exists on Fireworks AI; start route-level A/B tests there.
  • Llama 3.1 405B Instruct is $2.37/1M tokens higher on cheapest tracked output pricing, so quality gains need to justify the spend.
  • Llama 3.1 405B Instruct adds Structured outputs in local capability data.

Specs

Specification
Released2024-07-232024-07-18
Context window128k128k
Parameters405B12B
ArchitectureDecoder OnlyDecoder Only
LicenseLlama 3 CommunityApache 2.0OSI-approved
OpennessOpen weightsOpen source
Commercial useCommercial use: conditionalCommercial use: permitted
Knowledge cutoff2023-122024-04

Pricing and availability

Pricing attributeLlama 3.1 405B InstructMistral NeMo (2407)
Input price$2.40/1M tokens$0.02/1M tokens
Output price$2.40/1M tokens$0.03/1M tokens
Providers

Capabilities

CapabilityLlama 3.1 405B InstructMistral NeMo (2407)
VisionNoNo
MultimodalNoNo
ReasoningNoNo
Function callingNoNo
Tool useNoNo
Structured outputsYesNo
Code executionNoNo
IDE integrationNoNo
Computer useNoNo
Parallel agentsNoNo

Benchmarks

No shared benchmark scores are currently available for this pair.

Deep dive

The capability footprint differs most on structured outputs: Llama 3.1 405B Instruct. Both models share the core language-model surface, so the practical split is not just feature count. Use those differences to decide whether the page is about raw model quality, agentic coding support, multimodal ingestion, or predictable structured API behavior.

For cost, Llama 3.1 405B Instruct lists $2.40/1M input and $2.40/1M output tokens on the cheapest tracked provider, while Mistral NeMo (2407) lists $0.02/1M input and $0.03/1M output tokens on the cheapest tracked provider. A 70/30 input-output blend puts Mistral NeMo (2407) lower by about $2.38 per million blended tokens. Availability is 11 providers versus 7, so concentration risk also matters.

Choose Llama 3.1 405B Instruct when provider fit and broader provider choice are central to the workload. Choose Mistral NeMo (2407) when provider fit and lower input-token cost are more important. For production, rerun your own prompts through the exact provider, region, and tool stack you plan to ship. This keeps the decision grounded in measurable tradeoffs instead of brand-level assumptions. It also helps separate model capability from provider packaging, which can change cost and latency.

FAQ

Which has a larger context window, Llama 3.1 405B Instruct or Mistral NeMo (2407)?

Llama 3.1 405B Instruct supports 128k tokens, while Mistral NeMo (2407) supports 128k tokens. That gap matters most for long documents, large codebases, retrieval-heavy agents, and conversations where earlier context must remain visible.

Which is cheaper, Llama 3.1 405B Instruct or Mistral NeMo (2407)?

Mistral NeMo (2407) is cheaper on tracked token pricing. Llama 3.1 405B Instruct costs $2.40/1M input and $2.40/1M output tokens. Mistral NeMo (2407) costs $0.02/1M input and $0.03/1M output tokens. Provider discounts or batch pricing can still change the final bill.

Is Llama 3.1 405B Instruct or Mistral NeMo (2407) open source?

Llama 3.1 405B Instruct is listed under Llama 3 Community. Mistral NeMo (2407) is listed under Apache 2.0. License labels affect whether you can self-host, redistribute weights, or rely only on hosted APIs, so confirm the upstream license before deployment.

Which is better for structured outputs, Llama 3.1 405B Instruct or Mistral NeMo (2407)?

Llama 3.1 405B Instruct has the clearer documented structured outputs signal in this comparison. If structured outputs is mission-critical, validate it against the provider endpoint because model-level support and API-level exposure can differ.

Where can I run Llama 3.1 405B Instruct and Mistral NeMo (2407)?

Llama 3.1 405B Instruct is available on OctoAI API (Deprecated), Together AI, Fireworks AI, IBM watsonx, and Scale AI GenAI Platform. Mistral NeMo (2407) is available on Mistral AI Studio, OpenRouter, Fireworks AI, Bitdeer AI, and SiliconFlow. Provider coverage can affect latency, region availability, compliance posture, and fallback options.

When should I pick Llama 3.1 405B Instruct over Mistral NeMo (2407)?

Mistral NeMo (2407) is ~11900% cheaper at $0.02/1M; pay for Llama 3.1 405B Instruct only for provider fit. If your workload also depends on provider fit, start with Llama 3.1 405B Instruct; if it depends on provider fit, run the same evaluation with Mistral NeMo (2407).

Continue comparing

Last reviewed: 2026-06-15. Data sourced from public model cards and provider documentation.