LLM Reference

Claude Opus 4.5 vs Qwen3.5-122B-A10B

Claude Opus 4.5 (2025) and Qwen3.5-122B-A10B (2026) are frontier-tier reasoning models from Anthropic and Alibaba. Claude Opus 4.5 ships a 200k-token context window, while Qwen3.5-122B-A10B ships a 262k-token context window. On MMLU PRO, Claude Opus 4.5 leads by 2.2 pts. On pricing, Qwen3.5-122B-A10B costs $0.26/1M input tokens versus $5/1M for the alternative. This comparison covers specs, pricing, API access, capabilities, benchmarks, input and output token costs, and production fit for coding and agent workloads.

Qwen3.5-122B-A10B is ~1823% cheaper at $0.26/1M; pay for Claude Opus 4.5 only for coding workflow support.

Decision scorecard

Local evidence first
SignalClaude Opus 4.5Qwen3.5-122B-A10B
Best forreasoning-heavy apps, multimodal apps, and tool-calling agentsreasoning-heavy apps, multimodal apps, and tool-calling agents
Decision fitCoding, RAG, and AgentsCoding, RAG, and Agents
Context window200k262k
Cheapest output$25/1M tokens$2.08/1M tokens
Provider routes6 tracked3 tracked
Shared benchmarksMMLU PRO leader4 shared

Decision tradeoffs

Choose Claude Opus 4.5 when...
  • Claude Opus 4.5 holds a shared-benchmark lead on MMLU PRO, ahead by 2.2 points.
  • Claude Opus 4.5 has broader tracked provider coverage for fallback and route flexibility.
  • Claude Opus 4.5 uniquely exposes Code execution in local model data.
  • Local decision data tags Claude Opus 4.5 for Coding, RAG, and Agents.
Choose Qwen3.5-122B-A10B when...
  • Qwen3.5-122B-A10B holds a shared-benchmark lead on MMMU Pro, ahead by 3 points.
  • Qwen3.5-122B-A10B has the larger context window for long prompts, retrieval packs, or transcript analysis.
  • Qwen3.5-122B-A10B has the lower cheapest tracked output price at $2.08/1M tokens.
  • Local decision data tags Qwen3.5-122B-A10B for Coding, RAG, and Agents.

Monthly cost at traffic

Estimate token spend from the cheapest tracked input and output route or tier on this page.

Lower estimate Qwen3.5-122B-A10B

Claude Opus 4.5

$10,250

Cheapest tracked route/tier: Microsoft Foundry

Qwen3.5-122B-A10B

$728

Cheapest tracked route/tier: OpenRouter

Estimated monthly gap: $9,522. Batch, cache, alternate speed tiers, and negotiated pricing are excluded from this local estimate.

Switch friction

Claude Opus 4.5 -> Qwen3.5-122B-A10B
  • Provider overlap exists on OpenRouter; start route-level A/B tests there.
  • Qwen3.5-122B-A10B is $22.92/1M tokens lower on cheapest tracked output pricing before cache, batch, or negotiated discounts.
  • Check replacement coverage for Code execution before moving production traffic.
Qwen3.5-122B-A10B -> Claude Opus 4.5
  • Provider overlap exists on OpenRouter; start route-level A/B tests there.
  • Claude Opus 4.5 is $22.92/1M tokens higher on cheapest tracked output pricing, so quality gains need to justify the spend.
  • Claude Opus 4.5 adds Code execution in local capability data.

Specs

Specification
Released2025-11-012026-02-24
Context window200k262k
Parameters—122B
ArchitectureDecoder OnlyMixture of Experts
LicenseProprietaryApache 2.0OSI-approved
OpennessProprietaryOpen source
WeightsNot releasedAvailable
CodeUnknownUnknown
Commercial useCommercial use: conditionalCommercial use: permitted
Knowledge cutoff2025-12-

Pricing and availability

Pricing attributeClaude Opus 4.5Qwen3.5-122B-A10B
Input price$5/1M tokens$0.26/1M tokens
Output price$25/1M tokens$2.08/1M tokens
Providers
Microsoft FoundryAnthropicGCP Vertex AIAWS BedrockOpenRouterVercel AI Gateway
OpenRouterAlibaba Cloud PAI-EASNovita AI

Capabilities

CapabilityClaude Opus 4.5Qwen3.5-122B-A10B
VisionYesYes
MultimodalYesYes
ReasoningYesYes
JSON / Tool useYesYes
Structured outputsYesYes
Code executionYesNo
IDE integrationNoNo
Computer useNoNo
Parallel agentsNoNo

Benchmarks

BenchmarkClaude Opus 4.5Qwen3.5-122B-A10B
MMLU PRO88.986.7
SWE-bench Verified80.972.0
Google-Proof Q&A87.085.7
MMMU Pro73.976.9

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Last reviewed: 2026-07-26. Data sourced from public model cards and provider documentation.