Mixtral 8x22B Instruct v0.3 on Replicate API

Mixtral · MistralAI

ServerlessOpen Source

Last refreshed 2026-09-22. Next refresh: weekly.

Why use Mixtral 8x22B Instruct v0.3 on Replicate API?

Replicate API offers Mixtral 8x22B Instruct v0.3 with pay-as-you-go pricing at $2.00/1M input tokens. Replicate is a cloud-based platform that enables users to run machine learning models easily and efficiently.

Input / 1M
$2.00
Output / 1M
$2.00
Cache
Not sourced
Batch
Not sourced

Setup recipe

Python + curl
Install
pip install replicate
Auth
export REPLICATE_API_TOKEN=...
Call
import replicate
output = replicate.run(
    "mixtral-8x22b-instruct-v0.3",
    input={"prompt": "Hello"}
Model ID
mixtral-8x22b-instruct-v0.3

Request example

import replicate

# reads REPLICATE_API_TOKEN from env
# mixtral-8x22b-instruct-v0.3 format: "owner/model-name" (latest version) or "owner/model-name:version-hash"
output = replicate.run(
    "mixtral-8x22b-instruct-v0.3",
    input={"prompt": "Hello"}
)
# Output is a list or generator depending on the model
print("".join(output))

Gotchas

  • Replicate uses "owner/model-name" format (e.g. "meta/meta-llama-3-8b-instruct") for the latest version, or "owner/model-name:version-sha" to pin to a specific version. The REST endpoint splits owner and model-name into the path: /v1/models/{owner}/{model-name}/predictions.
  • The examples expect REPLICATE_API_TOKEN; rename it only if your application config maps the new variable.

Pricing

TypePrice (per 1M)
Input tokens$2.00
Output tokens$2.00

Capabilities

JSON / Tool use

About Mixtral 8x22B Instruct v0.3

Updated instruction-tuned Mixtral 8x22B MoE model from Mistral AI. Version 0.3 with improved instruction following and function calling capabilities.

Get Started

Model Specs

Released2024-07-01
Parameters8x22B
Context64k
ArchitectureMixture of Experts
Knowledge cutoff2024-01

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