Using Qwen2.5-72B-Instruct on Replicate API

Implementation guide · Qwen2.5 · Alibaba

ServerlessOpen Source

Replicate API exposes Qwen2.5-72B-Instruct through model ID qwen2.5-72b-instruct. Use the setup steps, sourced pricing, capabilities, and official provider links below to validate this route before deployment.

Last refreshed 2026-04-19. Next refresh: weekly.

Quick Start

  1. 1
    Create an account at Replicate API and generate an API key.
  2. 2
    Use the Replicate API SDK or REST API to call qwen2.5-72b-instruct — see the documentation for request format.
  3. 3
    You'll be billed $1.30/1M input, $1.30/1M output tokens. See full pricing.

Code Examples

Install
pip install replicate
API key
REPLICATE_API_TOKEN
Model ID
qwen2.5-72b-instruct

Replicate uses "owner/model-name" format (e.g. "meta/meta-llama-3-8b-instruct") for the latest version, or "owner/model-name:version-sha" to pin to a specific version. The REST endpoint splits owner and model-name into the path: /v1/models/{owner}/{model-name}/predictions.

import replicate

# reads REPLICATE_API_TOKEN from env
# qwen2.5-72b-instruct format: "owner/model-name" (latest version) or "owner/model-name:version-hash"
output = replicate.run(
    "qwen2.5-72b-instruct",
    input={"prompt": "Hello"}
)
# Output is a list or generator depending on the model
print("".join(output))

Pricing on Replicate API

TypePrice (per 1M)
Input tokens$1.30
Output tokens$1.30

Capabilities

Structured Outputs

About Qwen2.5-72B-Instruct

Instruction-optimized flagship variant for demanding production applications requiring high-accuracy complex problem-solving across industries.

Model Specs

Released2024-06-07
Parameters72.7B
Context128k
ArchitectureDecoder Only

Provider

Replicate API

Replicate

San Francisco, California, United States