Mistral Large 2 vs Qwen2.5-72B-Instruct
Mistral Large 2 (2025) and Qwen2.5-72B-Instruct (2024) are compact production models from MistralAI and Alibaba. Mistral Large 2 ships a 128k-token context window, while Qwen2.5-72B-Instruct ships a 128k-token context window. On HumanEval, Qwen2.5-72B-Instruct leads by 1.8 pts. On pricing, Qwen2.5-72B-Instruct costs $0.18/1M input tokens versus $0.48/1M for the alternative. This comparison covers specs, pricing, API access, capabilities, benchmarks, input and output token costs, and production fit for coding and agent workloads.
Qwen2.5-72B-Instruct is ~167% cheaper at $0.18/1M; pay for Mistral Large 2 only for vision-heavy evaluation.
Decision scorecard
Local evidence first| Signal | Mistral Large 2 | Qwen2.5-72B-Instruct |
|---|---|---|
| Best for | multimodal apps, tool-calling agents, and provider-routed production | provider-routed production |
| Decision fit | Coding, RAG, and Agents | Coding, RAG, and Long context |
| Context window | 128k | 128k |
| Cheapest output | $2.40/1M tokens | $0.54/1M tokens |
| Provider routes | 3 tracked | 7 tracked |
| Shared benchmarks | 4 shared | HumanEval leader |
Decision tradeoffs
- Mistral Large 2 uniquely exposes Vision, Multimodal, and JSON / Tool use in local model data.
- Local decision data tags Mistral Large 2 for Coding, RAG, and Agents.
- Qwen2.5-72B-Instruct holds a shared-benchmark lead on HumanEval, ahead by 1.8 points.
- Qwen2.5-72B-Instruct has the lower cheapest tracked output price at $0.54/1M tokens.
- Qwen2.5-72B-Instruct has broader tracked provider coverage for fallback and route flexibility.
- Local decision data tags Qwen2.5-72B-Instruct for Coding, RAG, and Long context.
Monthly cost at traffic
Estimate token spend from the cheapest tracked input and output route or tier on this page.
Mistral Large 2
$984
Cheapest tracked route/tier: AWS Bedrock
Qwen2.5-72B-Instruct
$279
Cheapest tracked route/tier: Chutes AI
Estimated monthly gap: $705. Batch, cache, alternate speed tiers, and negotiated pricing are excluded from this local estimate.
Switch friction
- No overlapping tracked provider route is sourced for Mistral Large 2 and Qwen2.5-72B-Instruct; plan for SDK, billing, or endpoint changes.
- Qwen2.5-72B-Instruct is $1.86/1M tokens lower on cheapest tracked output pricing before cache, batch, or negotiated discounts.
- Check replacement coverage for Vision, Multimodal, and JSON / Tool use before moving production traffic.
- No overlapping tracked provider route is sourced for Qwen2.5-72B-Instruct and Mistral Large 2; plan for SDK, billing, or endpoint changes.
- Mistral Large 2 is $1.86/1M tokens higher on cheapest tracked output pricing, so quality gains need to justify the spend.
- Mistral Large 2 adds Vision, Multimodal, and JSON / Tool use in local capability data.
Specs
| Specification | ||
|---|---|---|
| Released | 2025-11-25 | 2024-06-07 |
| Context window | 128k | 128k |
| Parameters | 123B | 72.7B |
| Architecture | Decoder Only | Decoder Only |
| License | Mistral License | Apache 2.0OSI-approved |
| Openness | Open weights | Open source |
| Weights | Unknown | Available |
| Code | Unknown | Unknown |
| Commercial use | Commercial use: non-commercial | Commercial use: permitted |
| Knowledge cutoff | 2025-07 | - |
Pricing and availability
| Pricing attribute | Mistral Large 2 | Qwen2.5-72B-Instruct |
|---|---|---|
| Input price | $0.48/1M tokens | $0.18/1M tokens |
| Output price | $2.40/1M tokens | $0.54/1M tokens |
| Providers |
Capabilities
| Capability | Mistral Large 2 | Qwen2.5-72B-Instruct |
|---|---|---|
| Vision | Yes | No |
| Multimodal | Yes | No |
| Reasoning | No | No |
| JSON / Tool use | Yes | No |
| Structured outputs | Yes | Yes |
| Code execution | No | No |
| IDE integration | No | No |
| Computer use | No | No |
| Parallel agents | No | No |
Benchmarks
| Benchmark | Mistral Large 2 | Qwen2.5-72B-Instruct |
|---|---|---|
| HumanEval | 84.8 | 86.6 |
| Chatbot Arena | 1265.0 | 1270.0 |
| Massive Multitask Language Understanding | 84.0 | 88.2 |
| HellaSwag | 93.8 | 95.6 |
Continue comparing
- Mistral Large 2 vs Qwen2.5-72B
- Mistral Large 3 675B Instruct vs Qwen2.5-72B
- Mistral Large 2.1 (2411) vs Qwen2.5-72B-Instruct
- Llama 3.3 70B Instruct (free) vs Qwen2.5-72B-Instruct
- Llama 3.3 70B vs Qwen2.5-72B-Instruct
- Qwen2.5-72B-Instruct vs Qwen3.6-27B
- DeepSeek R1 vs Qwen2.5-72B-Instruct
- Llama 3 70B Instruct vs Qwen2.5-72B-Instruct
- Mistral Large 2 vs Mixtral 8x7B
Popular comparisons for Mistral Large 2
Popular comparisons for Qwen2.5-72B-Instruct
Last reviewed: 2026-06-30. Data sourced from public model cards and provider documentation.