Mistral Large 3 675B Instruct vs Qwen2.5-72B
Mistral Large 3 675B Instruct (2025) and Qwen2.5-72B (2025) are compact production models from MistralAI and Alibaba. Mistral Large 3 675B Instruct ships a 128k-token context window, while Qwen2.5-72B ships a 128k-token context window. On MMLU PRO, Mistral Large 3 675B Instruct leads by 13.5 pts. This comparison covers specs, pricing, API access, capabilities, benchmarks, input and output token costs, and production fit for coding and agent workloads.
Mistral Large 3 675B Instruct is safer overall; choose Qwen2.5-72B when provider fit matters.
Decision scorecard
Local evidence first| Signal | Mistral Large 3 675B Instruct | Qwen2.5-72B |
|---|---|---|
| Best for | multimodal apps and provider-routed production | tool-calling agents |
| Decision fit | Coding, RAG, and Agents | RAG, Agents, and Long context |
| Context window | 128k | 128k |
| Cheapest output | $1.50/1M tokens | - |
| Provider routes | 6 tracked | 0 tracked |
| Shared benchmarks | MMLU PRO leader | 1 shared |
Decision tradeoffs
- Mistral Large 3 675B Instruct holds a shared-benchmark lead on MMLU PRO, ahead by 13.5 points.
- Mistral Large 3 675B Instruct has broader tracked provider coverage for fallback and route flexibility.
- Mistral Large 3 675B Instruct uniquely exposes Vision, Multimodal, and Structured outputs in local model data.
- Local decision data tags Mistral Large 3 675B Instruct for Coding, RAG, and Agents.
- Qwen2.5-72B uniquely exposes JSON / Tool use in local model data.
- Local decision data tags Qwen2.5-72B for RAG, Agents, and Long context.
Monthly cost at traffic
Estimate token spend from the cheapest tracked input and output route or tier on this page.
Mistral Large 3 675B Instruct
$775
Cheapest tracked route/tier: OpenRouter
Qwen2.5-72B
Unavailable
No complete token price in local provider data
Cost delta unavailable until both models have sourced input and output token prices.
Switch friction
- No overlapping tracked provider route is sourced for Mistral Large 3 675B Instruct and Qwen2.5-72B; plan for SDK, billing, or endpoint changes.
- Check replacement coverage for Vision, Multimodal, and Structured outputs before moving production traffic.
- Qwen2.5-72B adds JSON / Tool use in local capability data.
- No overlapping tracked provider route is sourced for Qwen2.5-72B and Mistral Large 3 675B Instruct; plan for SDK, billing, or endpoint changes.
- Check replacement coverage for JSON / Tool use before moving production traffic.
- Mistral Large 3 675B Instruct adds Vision, Multimodal, and Structured outputs in local capability data.
Specs
| Specification | ||
|---|---|---|
| Released | 2025-12-01 | 2025-10-10 |
| Context window | 128k | 128k |
| Parameters | 675B | 72B |
| Architecture | Decoder Only | - |
| License | Apache 2.0OSI-approved | Apache 2.0OSI-approved |
| Openness | Open source | Open source |
| Weights | Unknown | Available |
| Code | Unknown | Unknown |
| Commercial use | Commercial use: permitted | Commercial use: permitted |
| Knowledge cutoff | 2024-11 | 2024-09 |
Pricing and availability
| Pricing attribute | Mistral Large 3 675B Instruct | Qwen2.5-72B |
|---|---|---|
| Input price | $0.50/1M tokens | - |
| Output price | $1.50/1M tokens | - |
| Providers | - |
Capabilities
| Capability | Mistral Large 3 675B Instruct | Qwen2.5-72B |
|---|---|---|
| Vision | Yes | No |
| Multimodal | Yes | No |
| Reasoning | No | No |
| JSON / Tool use | No | Yes |
| Structured outputs | Yes | No |
| Code execution | No | No |
| IDE integration | No | No |
| Computer use | No | No |
| Parallel agents | No | No |
Benchmarks
| Benchmark | Mistral Large 3 675B Instruct | Qwen2.5-72B |
|---|---|---|
| MMLU PRO | 85.5 | 72.0 |
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Last reviewed: 2026-06-29. Data sourced from public model cards and provider documentation.